CAS:433-06-7，2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE

The invention relates to the technical field of batteries, in particular to an electrolyte containing an anti-overcharge additive and a lithium ion battery. The electrolyte comprises a lithium salt, an organic solvent and an anti-overcharge additive, the structural formula of the anti-overcharge additive is as shown in formula 1, in the formula, R1 is fluorine-containing alkyl with 1-5 carbon atoms, and R2 is hydrogen or alkyl with 1-5 carbon atoms. By adopting the anti-overcharge additive, the property of a negative electrode interface SEI film is optimized, and the lithium ion transmission resistance is increased, so that the anti-overcharge function is realized, and the mixed lithium salt of lithium bis (fluorosulfonyl) imide and lithium hexafluorophosphate is combined, so that the stability of the electrolyte is enhanced, and the safety performance of the lithium ion battery is improved; and ethylene sulfate is adopted as an SEI film-forming protective agent to assist in forming a smooth and uniform SEI film, and meanwhile, the SEI film can be decomposed when charged at high temperature, so that the overcharge performance is optimized.

The embodiment of the present invention provides an electrolyte, a secondary battery and an electrical device, wherein in the electrolyte provided in the embodiment of the present invention, the sulfonate additive with formula (I.) structure has good film-forming stability, can effectively reduce the contact between the cathode material and the electrolyte, and reduce the oxidative decomposition of the electrolyte gas production; The anhydride additives with formula (II.) structure can preferentially react with the trace water and hydrofluoric acid in the electrolyte, inhibit the hydrolysis of sodium salt, reduce the influence of its products on the positive and negative electrode materials, thereby improving the cycling and storage performance of the battery, thus improving the electrolyte of the sodium-ion battery is easy to redox on the surface of the positive and negative electrodes to generate complex gases, resulting in the decomposition of sodium salts, affecting the cycle and storage performance of the battery.

Cyclooxygenase-1 (COX-1) and its isozyme COX-2 are key enzymes in the syntheses of prostanoids. Imaging of COX-1 and COX-2 selective radioligands with positron emission tomography (PET) may clarify how these enzymes are involved in inflammatory conditions and assist in the discovery of improved anti-inflammatory drugs. We have previously labeled the selective high-affinity COX-1 ligand, 1,5-bis(4-methoxyphenyl)-3-(2,2,2-trifluoroethoxy)-1H-1,2,4-triazole (PS13), with carbon-11 (t1/2 = 20.4 min). This radioligand ([11C]PS13) has been successful for PET imaging of COX-1 in monkey and human brain and in periphery. [11C]PS13 is being used in clinical investigations. Alternative labeling of PS13 with fluorine-18 (t1/2 = 109.8 min) is desirable to provide a longer-lived radioligand in high activity that might be readily distributed among imaging centers. However, labeling of PS13 in its 1,1,1-trifluoroethoxy group is a radiochemical challenge. Here we assess two labeling approaches based on nucleophilic addition of cyclotron-produced [18F]fluoride ion to gemdifluorovinyl precursors, either to label PS13 in one step or to produce [18F]2,2,2-trifluoroethyl p-toluenesulfonate for labeling a hydroxyl precursor. From the latter two-step approach, we obtained [18F]PS13 ready for intravenous injection in a decay-corrected radiochemical yield of 7.9% and with a molar activity of up to 7.9 GBq/μmol. PET imaging of monkey brain with [18F]PS13 shows that this radioligand can specifically image and quantify COX-1 without radiodefluorination but with some radioactivity uptake in skull, ascribed to red bone marrow. The development of a new procedure for labeling PS13 with fluorine-18 at a higher molar activity is, however, desirable to suppress occupancy of COX-1 by carrier at baseline.