Fluorine intermediates

CAS:186204-66-0，2-((Difluoromethyl)sulfonyl)benzo[d]thiazole

Specification：95%
Properties：solid
Package：fluorinated bottle
Usage：Pharmaceutical intermediates
Product description: CAS: 186204-66-0 | product name: 2 groups (2 - benzothiazole) sulfone 95%, alias: DSBT
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Difluoromethyl (2-benzothiazolyl) sulfone basic information

Chinese name: difluoromethyl (2-benzothiazolyl) sulfone

Difluoromethyl (2-benzothiazolyl) sulfone; 2-((difluoromethyl) sulfonyl) benzo [D] thiazole; 2-[(difluoromethyl) sulfonyl] benzothiazole; Difluoromethylbenzothiazolsulfone; (2)-(difluoromethyl) sulfonyl benzothiazole (D); 3-difluoromethyl sulfone benzothiazole; 2-difluoromethyl sulfone benzothiazole; 2-fluoromethyl sulfone benzothiazole

English name: 2-((Difluoromethyl)sulfonyl)benzo[d]thiazole,98%

2-(Difluoromethyl)sulfChemicalbookonyl)benzo[d]thiazole,98%; 2-[(Difluoromethyl)sulfonyl]benzothiazole; Benzothiazole,2-[(difluoromethyl)sulfonyl]-; 2-Benzo[d]thiazolyldifluoromethylsulfone

CAS number: 186204-66-0

Molecular formula: C8H5F2NO2S2

Molecular weight: 249.26

Related category: Chemical raw materials

Mol File: 186204-66-0.mol

Visible-light induced photocatalyst-free difluoromethylation of quinoxalinones with difluorosulfones

Shi, Linlin; Li, Tiantian; Zhang, Wenjing; Hu, Weinan; Zhu, Xinju; Lu, Yixin; Mei, Guang-Jian [Green Synthesis and Catalysis, 2023]

Abstract

Visible-light induced direct C–H difluoromethylation of quinoxalinones with 2-((difluoromethyl)sulfonyl)benzo[d]thiazole has been developed for the first time. A broad range of quinoxalinones were well tolerated and reacted with difluorosulfone smoothly to give the corresponding products in moderate to good yields. Notably, no external photocatalyst or oxidant was required, which provides a practical and green protocol to access difluoromethylated quinoxalinones. Finally, the control experiments demonstrated a radical mechanism, and the density functional theory (DFT) calculations indicated the radicals were generated through the formation of an electron donor−acceptor (EDA) complex.

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